Aldolase

## General Information (more on wikipidia)

 Molecular Weight (g/mol) Density (g/L) Radius (m) Reference Species Aldolase MW D R [1]

Aldolase A is an enzyme which catalyses one of the aldol reactions: The substrate, fructose 1,6-bisphosphate (F-1,6-BP) is broken down into glyceraldehyde 3-phosphate and dihydroxyacetone phosphate (DHAP). This reaction is a part of glycolysis.

In mammalian aldolase the key catylitic amino acid residues involved in the reaction are lysine and tyrosine. The tyrosine acts as an efficient hydrogen acceptor while the lysine covalently binds and stabilizes the intermediates. Many bacteria use two magnesium ions in place of the lysine.

## Diffusion of Aldolase in water:

• Alone:
• FITC-BSA : $D = 40.7 \ \mu m^{2} s^{-1}$ [1]
Bibliography
1. Proceedings of the National Academy of Sciences of the United States of America, Vol. 85, No. 9. (May 1, 1988), pp. 2984-2988