General Information (more on wikipidia)

Species Molecular Weight (g/mol) Density (g/L) Radius (m) Reference
Threonine 119.12 D R [1]

Threonine is an α-amino acid with the chemical formula HO2CCH(NH2)CH(OH)CH3. Its three letter code is thr, its one letter code is T, and its codons are ACU and ACA. This essential amino acid is classified as polar. Together with serine and tyrosine, threonine is one of three proteinogenic amino acids bearing an alcohol group.
The threonine residue is susceptible to numerous posttranslational modifications. The hydroxy side chain can undergo O-linked glycosylation. Additionally, threonine residues undergo phosphorylation through the action of a threonine kinase. In its phosphorylated form, it can be referred to as phosphothreonine.

As an essential amino acid, threonine is not synthesized in humans, hence we must ingest threonine or, more commonly, threonine-containing proteins. In plants and microorganisms, threonine is synthesized from aspartic acid via α-aspartyl-semialdehyde and homoserine. Homoserine undergoes O-phosphorylation; this phosphate ester undergoes hydrolysis concomitant with relocation of the OH group.

Diffusion of in water:

  • Alone at 25 degrees: $D = 800 \ \mu m^{2} s^{-1}$ [1]

Diffusion of in PBS:

  • $D = \ \mu m^{2} s^{-1}$

Diffusion of in cellular matrix:

  • $D = \ \mu m^{2} s^{-1}$
1. Longsworth, L. G. 1955. Diffusion in liquids and the Stokes-Einstein relation, p. 225-247. In T. Shedlovsky (ed.), Electrochemistry in biology and medicine. John Wiley & Sons, Inc., New York, N.Y.
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